Misuse of the reformulated drug is not impossible, but it is more difficult, said Simon H. Budman, PhD. […]
He compared the traditional oxycodone pill to aspirin — easy to crush. The tamper-resistant pill is more like Skittles candy when smashed. […]
Among opioid-abusing patients seeking treatment for substance-use disorders, misuse of extended-release oxycodone fell by half after a reformulated, abuse-resistant version came on the market in August 2010. Oral and nonoral forms of abuse declined.
More by Kevin O’Reilly in American Medical News. Relevant peer-reviewed studies in NEJM and The Journal of Pain. (Is there a better titled medical journal?)