Tamper-resistant opioids

Misuse of the reformulated drug is not impossible, but it is more difficult, said Simon H. Budman, PhD. […]

He compared the traditional oxycodone pill to aspirin — easy to crush. The tamper-resistant pill is more like Skittles candy when smashed. […]

Among opioid-abusing patients seeking treatment for substance-use disorders, misuse of extended-release oxycodone fell by half after a reformulated, abuse-resistant version came on the market in August 2010. Oral and nonoral forms of abuse declined.

More by Kevin O’Reilly in American Medical News. Relevant peer-reviewed studies in NEJM and The Journal of Pain. (Is there a better titled medical journal?)

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Austin Frakt

Austin Frakt, PhD, is co-Editor-in-Chief of The Incidental Economist. His day job is Associate Director of the Partnered Evidence-based Policy Resource Center at the Boston VA Healthcare System, U.S. Department of Veterans Affairs. He is also a Professor with the Department of Health Law, Policy and Management at the Boston University’s School of Public Health, a Principal Research Scientist with the Department of Health Policy and Management at the Harvard T.H. Chan School of Public Health, and Editor-in-Chief of the journal Health Services Research.

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